Recombinant stable cell lines are one of the widely used tools in drug discovery, toxicity testing, and basic research. Long-term stable expression of a gene of interest (GOI) is usually achieved by transfection or viral transduction of a vector containing the expression cassette of the GOI together with a selection marker (antibiotics or fluorescent proteins). In contrast to transient expression, stable cell line offers reproducible results for assay studies.
Advantages Stable Cell Line Services
1. Multiple gene transfer methods available: Both virus (lentivirus or retrovirus) and non-virus (chemical or physical) based options
2. Track record of handling difficult-to-transfect cell lines
3. Experience in stably expressing membrane proteins
4. High quality standards for mycoplasma control and detection
5. Guaranteed mRNA expression
6. Multiple functional assay methods for clone validation
7. One-stop solution for drug discovery: From gene synthesis to cell development